Art,
I know on many models you can set the PCL defaults (EX: Two Sided & Duplex). These will be ignored when you print form a PCL Driver because the Driver will over ride the defaults. But if they print from a host system the MFD PCL defaults will be used.
The other thing you can propose,(Most Host Admins will hate the idea) is set up a Windows Print Driver on a Windows Server. make sure LPD is running and set the Printing Preferences (I also set the Printing Defaults) to DX & Staple and have the Host Print to the printer on the Windows Print server to pick up the desired settings.
Hope that helps!
Vince